The application-specific permission settings do not grant Local Activation permission for the COM Server application with CLSID{61738644-F196-11D0-995

http://community.spiceworks.com/windows_event/show/84-dcom-10016

My issue was related to an IIS service

following is the resolution from the above link:

1. Open the registry and go to "HKEY_CLASSES_ROOT\CLSID\{} to find out friendly name of this component. In my case, this is "Machine Debug Manager” (CLSID: 0C0A3666-30C9-11D0-8F20-00805F2CD064).

2. Go to Component Services via Start -> Control Panel -> Administrative Tools -> Components Services. Expand the Component Services branch then expand "Computers", "My Computer", and "DCOM Config". Right-click on "Machine Debug Manager" (or whatever your CLSID represents) and choose Properties. Click on the Security tab and under “Launch and Activation Permissions” select "Use Default". Click OK, close the Component Services window. The error should disappear now.